ACTIVE
INGREDIENT
Each
100ml contains:
Sodium
chloride : 15g
3-methyl-6-isopropylphenol
( preservative ) : 0.001g
PHARMACODYNAMICS
Sodium
salt act by retaining fluid in the bowel by osmosis or by changing the pattern
of water distribution in faeces.
PHARMACOKINETICS
Sodium
chloride is readily absorbed from the gastrointestinal tract. It is present in
all the body fluids and is mainly found in the extra cellular fluid. The amount
of sodium chloride lost in sweat is small and the osmotic equilibrium is
maintained by the excretion of surplus amounts in the urine.
ADVERSE
EFFECTS
Enema
can cause rectal irritations, which are characterized by rectal bleeding,
blistering, burning, itching or pain. There can also be skin irritation
surrounding the rectal area.
WARNINGS/PRECAUTION
Enemas
should be used with caution in the elderly and should not be used by people
with acute gastrointestinal conditions or inflammatory bowel disease. Enemas
should not be used in patients with congenital megacolon, bowel obstruction,
imperforate anus or congestive heart failure. Use with caution in patients with
impaired renal function, pre-existing electrolyte disturbances or in patients
on diuretics or other medications which may affect electrolyte levels or where
colostomy exists. Since enema contains sodium chloride, there is a risk of
elevated serum levels of sodium and decreased levels of potassium and
consequent hypernatremia. This is of particular concern in children with
megacolon or any other condition where there is retention of enema solution.
CONTRAINDICATIONS
It
is contraindicated in patients with ileus, gastric retention, gastrointestinal
obstruction, bowel perforation, toxic colitis and toxic magacolon.
DRUG
INTERACTION
Not
known.
DOSAGE
& ADMINISTRATION
Rectally
used
Adults
: 20-40ml, once daily.
Children
: 10-20ml once daily
SYMPTOMS
OF OVERDOSAGE & TREATMENT
The
sign and symptoms would be the exaggeration of the side effects, especially
rectal irritation. The frequency of bowel movement would also be increased.
Treatment would be the cessation of use of the medication. If symptoms
continue, professional medical advise should be obtained.
STORAGE
Store
below 25°C in a cool dry place and protected from sunlight. keep out of reach
of children.
SHELF
LIFE
3
years
PACK
SIZE
10ml/bottle
& 20ml/bottle
PRODUCT
DESCRIPTION
A
colorless, clear and transparent solution
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